Toward Mechanistic Understanding of Mechanochemical Reactions Using Real-Time In Situ Monitoring

Stipe Lukin, Luzia S. Germann, Tomislav Friščić, and Ivan Halasz

https://doi.org/10.1021/acs.accounts.2c00062

Acc. Chem. Res. 2022 

Using Desmotropes, Cocrystals, and Salts to Manipulate Reactivity in Mechanochemical Organic Reactions

Magdalena Kralj, Stipe Lukin, Goran Miletić, Ivan Halasz

J. Org. Chem. 2021, 86, 14160–14168

Raman spectroscopy for real-time and in situ monitoring of mechanochemical milling reactions

S. Lukin, K. Užarević, I . Halasz

Nat. Protoc. (2021) 16, 3492–3521

Mechanochemical Metathesis between AgNO3 and NaX (X = Cl, Br, I) and Ag2XNO3 Double-Salt Formation

Stipe Lukin, Tomislav Stolar, Ivor Lončarić, Igor Milanović, Nikola Biliškov, Marco di Michiel, Tomislav Friščić, Ivan Halasz

Inorg. Chem. 2020, 59, 12200–12208

Mechanochemical Preparation of Active Pharmaceutical Ingredients Monitored by In Situ Raman Spectroscopy

Irena Sović, Stipe Lukin, Ernest Meštrović, Ivan Halasz, Andrea Porcheddu, Francesco Delogu, Pier Carlo Ricci, Fabien Caron, Thomas Perilli, Anita Dogan, Evelina Colacino

ACS Omega 2020, 5, 44, 28663–28672

Isotope Labeling Reveals Fast Atomic and Molecular Exchange in Mechanochemical Milling Reactions

S. Lukin, M. Tireli, T. Stolar, D. Barišić, M. V. Blanco, M. di Michiel, K. Užarević, I. Halasz

J. Am. Chem. Soc. 141 (2019) 1212–1216.

Mechanochemical carbon-carbon bond formation that proceeds via a cocrystals intermediate

S. Lukin, M. Tireli, I. Lončarić, D. Barišić, P. Šket, D. Vrsaljko, M. di Michiel, J. Plavec, K. Užarević, I.  Halasz

Chem. Commun. 54 (2018) 13216–13219.

Experimental and Theoretical Study of Selectivity in Mechanochemical Cocrystallization of Nicotinamide with Anthranillic and Salicylic Acid

S. Lukin, I. Lončarić, M. Tireli, T. Stolar, M. V. Blanco, P. Lazić, K. Užarević, I. Halasz

Cryst. Growth Des. 18 (2018) 1539–1547.

Enthalpy vs. friction: heat flow modelling of unexpected temperature profiles in mechanochemistry of metal–organic frameworks

K. Užarević, N. Ferdelji, T. Mrla, P. A. Julien, B. Halasz, T. Friščić, I. Halasz 

Chem. Sci. 2018, 9, 2525–2532.

In Situ Monitoring and Mechanism of the Mechanochemical Formation of a Microporous MOF–74 Framework

P. A. Julien, K. Užarević, A. D. Katsenic, S. A. J. Kimber, T. Wang, O. K. Farha, Y. Zhang, J. Casaban, L. S. Germann, M. Etter, R. E. Dinnebier, S. L. James, I. Halasz, T. Friščić

J. Am. Chem Soc. 138 (2016) 2929–2932.

Exploring the effect of temperature on a mechanochemical reaction by in situ synchrotron X-ray powder diffraction

Krunoslav Užarević, Vjekoslav Štrukil, Cristina Mottillo, Patrick A Julien, Andreas Puškarić, Tomislav Friščić, Ivan Halasz

Cryst. Growth Des. 2016, 16, 4, 2342–2347

Tandem in Situ Monitoring for Quantitative Assessment of Mechanochemical Reactions Involving Structurally Unknown Phases

S. Lukin, T. Stolar, M. Tireli, M. V. Blanco, D. Babić, T. Friščić, K. Užarević, I. Halasz

Chem. Eur. J. 23 (2017) 13941–13949.